the only factorization that can be done using this equation is writing it as a difference of squares
you can rewrite it as
[tex]x^4+4x^2+4=(x^2)^2+2\cdot x^2\cdot2+2^2[/tex]by deffinition of the difference of squares
[tex]x^{4^{}}+4x^2+4=(x^2+2)^2[/tex]